| Date | Location | Result | |
| Nov 11, 2010 | Springfield, Ohio | Heidelberg 3, Greenville 1 (25-15,23-25,25-14,25-18) | Box score |
| Nov 06, 2010 | Greenville, Ill. | Greenville 3, Webster 0 (25-15,25-16,25-20) | Box score |
| Nov 06, 2010 | Greenville, Ill. | Greenville 3, Principia 1 (25-21,25-23,17-25,26-24) | Box score |
| Nov 02, 2010 | Greenville, Ill. | Greenville 3, Fontbonne 0 (25-14,25-9,25-15) | Box score |
| Oct 30, 2010 | Fulton, Mo. | Greenville 3, Westminster (MO) 2 (25-17,17-25,21-25,25-15,16-14) | Box score |
| Oct 30, 2010 | Fulton, Mo. | Greenville 3, Principia 0 (25-16,25-15,25-16) | Box score |
| Oct 28, 2010 | Springfield, Ill. | Greenville 3, Robert Morris-S'fiel 0 (25-14,25-22,25-16) | Box score |
| Oct 26, 2010 | St. Louis, Mo. | Greenville 3, Webster 0 (25-19,25-15,28-26) | Box score |
| Oct 19, 2010 | Jacksonville, Ill. | Greenville 3, Illinois Col. 1 (25-18,18-25,25-21,25-20) | Box score |
| Oct 15, 2010 | Greenville, Ill. | Greenville 3, MacMurray 0 (25-13,25-18,25-10) | Box score |
| Oct 12, 2010 | Carlinville, Ill. | Greenville 3, Blackburn 0 (25-14,25-10,25-13) | Box score |
| Oct 09, 2010 | Elsah, Ill. | Greenville 3, Spalding 2 (25-13,18-25,25-17,19-25,15-13) | Box score |
| Oct 09, 2010 | Elsah, Ill. | Greenville 3, Eureka 0 (25-13,25-19,25-11) | Box score |
| Oct 07, 2010 | Springfield, Ill. | Greenville 3, Benedictine-Sprngfld 1 (25-19,15-25,25-20,25-21) | Box score |
| Oct 05, 2010 | Greenville, Ill. | Greenville 3, Westminster (MO) 0 (25-24,25-20,25-23) | Box score |
| Oct 02, 2010 | Greenville, Ill. | Greenville 3, Webster 1 (25-17,30-28,23-25,25-20) | Box score |
| Oct 02, 2010 | Greenville, Ill. | Greenville 3, Blackburn 0 (25-9,25-14,25-17) | Box score |
| Sep 30, 2010 | Galesburg, Ill. | Greenville 3, Knox 0 (25-20,25-15,25-9) | Box score |
| Sep 27, 2010 | Greenville, Ill. | Greenville 3, St. Louis Pharmacy 0 (25-15,25-19,25-23) | Box score |
| Sep 25, 2010 | Louisville, Ky. | Spalding 3, Greenville 1 (25-23,25-16,22-25,25-23) | Box score |
| Sep 25, 2010 | Louisville, Ky. | Rose-Hulman 3, Greenville 0 (25-14,25-19,25-17) | Box score |
| Sep 21, 2010 | Greenville, Ill. | Greenville 3, Principia 0 (25-11,25-13,25-22) | Box score |
| Sep 18, 2010 | St. Louis, Mo. | Greenville 3, Fontbonne 1 (25-18,19-25,25-20,25-16) | Box score |
| Sep 18, 2010 | St. Louis, Mo. | Greenville 3, MacMurray 0 (25-19,25-12,25-17) | Box score |
| Sep 14, 2010 | Eureka, Ill. | Greenville 3, Eureka 0 (25-11,25-17,25-12) | Box score |
| Sep 11, 2010 | Greenville, Ill. | Greenville 3, Knox 0 (25-16,27-25,25-22) | Box score |
| Sep 11, 2010 | Greenville, Ill. | Greenville 3, Robert Morris-S'fiel 1 (25-14,25-10,17-25,25-18) | Box score |
| Sep 07, 2010 | Greenville, Ill. | Greenville 3, Benedictine-Sprngfld 0 (25-21,25-13,25-11) | Box score |
| Sep 04, 2010 | Monmouth, Ill. | Monmouth (IL) 3, Greenville 0 (26-24,25-22,25-23) | Box score |
| Sep 04, 2010 | Monmouth, Ill. | Cornell College 3, Greenville 0 (25-14,25-18,25-20) | Box score |
| Sep 04, 2010 | Monmouth, Ill. | Greenville 3, MacMurray 1 (24-26,25-22,25-8,25-10) | Box score |
| Sep 01, 2010 | St. Louis, Mo. | Washington-St. Louis 3, Greenville 0 (25-15,25-17,25-18) | Box score |